SCHEMBL570907

SCHEMBL570907

CCC1(C)C(=O)N(C)C(=O)N1Br

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.32
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060736 0.81
SCHEMBL631587 0.81
SCHEMBL3907571 0.78
SCHEMBL3907491 0.78
SCHEMBL19923600 0.76 LMNA (0.32) ATMLMNA
SCHEMBL4442255 0.75
SCHEMBL7058181 0.73 LMNA (0.34) LMNA
SCHEMBL29207097 0.71 LMNA (0.33) LMNA
SCHEMBL19923727 0.71
SCHEMBL19923436 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7550622-B2 Cycloalkylamidoacid compounds, processes for making and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-23 US claimed
US-11192875-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2021-12-07 US disclosed
US-20200392100-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2020-12-17 US disclosed
US-10584109-B2 Processes for preparing antiviral compounds Gillead Pharmasset LLC (US) 2020-03-10 US disclosed
US-20190263771-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2019-08-29 US disclosed
US-20180179175-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC 2018-06-28 US disclosed
US-9890134-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2018-02-13 US disclosed
US-20170283390-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2017-10-05 US disclosed
US-9670187-B2 Processes for preparing antiviral compounds GILEAD PHARMASSET LLC (US) 2017-06-06 US disclosed
EP-3154984-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2017-04-19 EP disclosed
US-20150361073-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2015-12-17 US disclosed
WO-2015191437-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC (US) 2015-12-17 WO disclosed
US-20130274284-A1 PREPARATION OF PRASUGREL HYDROCHLORIDE DR. REDDY'S LABORATORIES, INC. (US) 2013-10-17 US disclosed
EP-2601200-A2 PREPARATION OF PRASUGREL HYDROCHLORIDE Dr. Reddy's Laboratories Ltd. (IN) 2013-06-12 EP disclosed
EP-1656340-B1 Processes for making 1-carbamoylcycloalkylcarboxylic acid compounds BOEHRINGER INGELHEIM INT (DE) 2012-07-18 EP disclosed
WO-2012018791-A2 PREPARATION OF PRASUGREL HYDROCHLORIDE DR. REDDY'S LABORATORIES LTD. (IN) 2012-02-09 WO disclosed
US-7550622-B2 Cycloalkylamidoacid compounds, processes for making and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-23 US disclosed
EP-1656340-A1 1-CARBAMOYLCYCLOALKYLCARBOXYLIC ACID COMPOUNDS, PROCESSES FOR MAKING AND USES THEREOF Boehringer Ingelheim International GmbH (DE) 2006-05-17 EP disclosed
US-20050085544-A1 Cycloalkylamidoacid compounds, processes for making and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-04-21 US disclosed
WO-2005019158-A1 1-CARBAMOYLCYCLOALKYLCARBOXYLIC ACID COMPOUNDS, PROCESSES FRO MAKING AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10584109-B2 Processes for preparing antiviral compounds MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885
US-11192875-B2 Processes for preparing antiviral compounds MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885
US-20170283390-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885
US-20130274284-A1 PREPARATION OF PRASUGREL HYDROCHLORIDE PFKP, PF4, PTAFR ATM 890/4885LMNA 2738/4885TSHR 3661/4885
US-20150361073-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885
US-20180179175-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885
US-20200392100-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885
US-20050085544-A1 Cycloalkylamidoacid compounds, processes for making and uses thereof ACMSD, QPCT, DCXR ATM 1616/4885LMNA 3389/4885TSHR 3727/4885
US-20190263771-A1 PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SAMHD1 ATM 2741/4885LMNA 2870/4885TSHR 4459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.