Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709432 | 0.93 | OPRM1 (0.55) | OPRM1CHRM2CHRM3SIGMAR1DRD2 | |
| SCHEMBL27654948 | 0.82 | CCR5 (0.41) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL5709507 | 0.79 | OPRM1 (0.52) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL5709427 | 0.77 | OPRM1 (0.64) | OPRM1CHRM2CHRM3SIGMAR1DRD2 | |
| SCHEMBL5709506 | 0.76 | SIGMAR1 (0.50) | OPRM1SIGMAR1CCR5 | |
| SCHEMBL5709465 | 0.76 | OPRM1 (0.48) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| SCHEMBL3937369 | 0.74 | ACHE (0.54) | KCNH2CACNA1I | |
| SCHEMBL5709408 | 0.74 | ACHE (0.59) | OPRM1CHRM2CHRM3SIGMAR1 | |
| SCHEMBL5709413 | 0.73 | OPRM1 (0.45) | OPRM1CHRM2CHRM3UBE2MDCUN1D1 | |
| Hydrochloric Acid SCHEMBL1814858 | 0.73 | OPRM1 (0.62) | OPRM1CHRM2CHRM3SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |