Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19691811 | 0.94 | HRH3 (0.56) | FAAHBCHEACHESIGMAR1HRH3 | |
| SCHEMBL3592177 | 0.93 | FAAH (0.59) | FAAHBCHEACHELTA4HSIGMAR1 | |
| SCHEMBL19691871 | 0.89 | ACHE (0.67) | FAAHBCHEACHELTA4HSIGMAR1 | |
| SCHEMBL3594530 | 0.88 | LTA4H (0.53) | LTA4HHTR1AHTR7 | |
| SCHEMBL21004138 | 0.85 | SIGMAR1 (0.49) | FAAHBCHEACHELTA4HSIGMAR1 | |
| SCHEMBL28286477 | 0.84 | SIGMAR1 (0.56) | FAAHBCHEACHESIGMAR1HRH3 | |
| SCHEMBL3937347 | 0.84 | SIGMAR1 (0.55) | FAAHBCHEACHESIGMAR1HRH3 | |
| SCHEMBL21004145 | 0.83 | LTA4H (0.55) | FAAHBCHEACHELTA4HSIGMAR1 | |
| SCHEMBL19691823 | 0.83 | FAAH (0.66) | FAAHBCHEACHELTA4HSIGMAR1 | |
| SCHEMBL19691817 | 0.83 | FAAH (0.66) | FAAHBCHEACHELTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| US-10851053-B2 | Chemical compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-01 | — | — | US | disclosed |
| US-20190144384-A1 | Chemical Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
| EP-3468948-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-04-17 | — | — | EP | disclosed |
| WO-2017212423-A1 | CHEMCICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-12-14 | — | — | WO | disclosed |
| US-20100279998-A1 | PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2010-11-04 | — | — | US | disclosed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144384-A1 | Chemical Compounds | ATF4, EIF2B5, HSPA5 | FAAH 4384/4885BCHE 2621/4885ACHE 4289/4885 |
| US-20100279998-A1 | PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS | FAAH, FAAH2, CNR2 | FAAH 1/4885BCHE 120/4885ACHE 428/4885 |
| US-10851053-B2 | Chemical compounds | ATF4, EIF2B5, HSPA5 | FAAH 4384/4885BCHE 2621/4885ACHE 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.