Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TYMP | P19971 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL5147665 | 1.00 | TK1 (0.58) | TK1LMNATSHRALBBLM | |
| Phosphoric Acid SCHEMBL18249308 | 1.00 | TK1 (0.58) | TK1LMNATSHRALBBLM | |
| Phosphoric Acid SCHEMBL7977953 | 1.00 | TK1 (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL925743 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL22992337 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL14596607 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL13286394 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL762579 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL23485 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM | |
| SCHEMBL14421795 | 0.95 | LMNA (0.58) | TK1LMNATSHRALBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566953-B1 | METHODS FOR CONTROL OF FLUX IN METABOLIC PATHWAYS THROUGH ENZYME RELOCATION | GREENLIGHT BIOSCIENCES INC (US) | 2019-01-02 | — | — | EP | claimed |
| EP-3122756-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2017-02-01 | — | — | EP | claimed |
| WO-2015144282-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2015-10-01 | — | — | WO | claimed |
| EP-3122756-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015144282-A1 | INORGANIC-ORGANIC HYBRID COMPOUND | Karlsruher Institut für Technologie (DE) | 2015-10-01 | — | — | WO | disclosed |
| EP-1720976-B1 | METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL | INSILICO BIOTECHNOLOGY AG (DE) | 2014-10-08 | — | — | EP | disclosed |
| EP-1720976-A1 | METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL | Insilico Biotechnology Gmbh (DE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005083054-A1 | METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL | INSILICO BIOTECHNOLOGY GMBH (DE) | 2005-09-09 | — | — | WO | disclosed |