Phosphoric Acid

Phosphoric Acid

SCHEMBL5147665

Cc1cn([C@H]2CC[C@@H](CO)O2)c(=O)[nH]c1=O.O=P(O)(O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADRA1A known ✓ P35348 1/20 0.53
TK1 P04183 3/20 0.58
LMNA P02545 3/20 0.56
TSHR P16473 2/20 0.56
ALB P02768 2/20 0.56
BLM P54132 2/20 0.56
PKM P14618 1/20 0.56
PMP22 Q01453 1/20 0.56
CYP2D6 P10635 1/20 0.56
TYMP P19971 4/20 0.54
ALDH1A1 P00352 1/20 0.53
POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL5709986 1.00 TK1 (0.58) TK1LMNATSHRALBBLM
Phosphoric Acid SCHEMBL18249308 1.00 TK1 (0.58) TK1LMNATSHRALBBLM
Phosphoric Acid SCHEMBL7977953 1.00 TK1 (0.58) TK1LMNATSHRALBBLM
SCHEMBL925743 0.95 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL22992337 0.95 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL14596607 0.95 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL13286394 0.95 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL762579 0.95 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL23485 0.95 LMNA (0.58) TK1LMNATSHRALBBLM
SCHEMBL14421795 0.95 LMNA (0.58) TK1LMNATSHRALBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111936522-B Novel anti-thymidine kinase antibody 豪夫迈·罗氏有限公司 2024-07-02 CN disclosed
WO-2023143247-A1 LINKER FOR CHARACTERIZING SEQUENCING OF TARGET POLYNUCLEOTIDE, CONSTRUCT, METHOD, AND USE 成都齐碳科技有限公司 2023-08-03 WO disclosed
CN-111936522-A Novel anti-thymidine kinase antibodies 豪夫迈·罗氏有限公司 2020-11-13 CN disclosed
CN-110520128-A Compositions and methods for treating complications and diseases associated with von Willebrand factor BAND THERAPEUTICS LLC 2019-11-29 CN disclosed
CN-110168104-A METHODS AND SYSTEMS FOR CHARACTERIZING ANALYTES USING NANOPORES 牛津纳米孔技术公司 2019-08-23 CN disclosed
CN-110121562-A Method of producing a composite material 牛津纳米孔技术公司 2019-08-13 CN disclosed
CN-110088299-A Nanopore-directed nucleic acid detection methods 牛津纳米孔技术公司 2019-08-02 CN disclosed
CN-109328192-A Labeled polynucleotide composition and the method for nucleic acid sequencing 宽腾矽公司 2019-02-12 CN disclosed
CN-109312401-A The nano-pore sequencing method of the nucleic acid of connection 牛津纳米孔技术公司 2019-02-05 CN disclosed
CN-109219665-A Method 牛津纳米孔技术公司 2019-01-15 CN disclosed
US-20070179083-A1 Covalent attachment of ligands to nucleophilic proteins guided by non-covalent binding COVALENT BIOSCIENCE INCORPORATED 2007-08-02 US disclosed
EP-1610808-A2 COVALENT ATTACHMENT OF LIGANDS TO NUCLEOPHILIC PROTEINS GUIDED BY NON-COVALENT BINDING University of Texas Medical School (US) 2006-01-04 EP disclosed
CN-1216883-C Synthesis of anticancer medicine raltiprexed UNIV CAPITAL NORMAL (CN) 2005-08-31 CN disclosed
WO-2004087059-A2 COVALENT ATTACHMENT OF LIGANDS TO NUCLEOPHILIC PROTEINS GUIDED BY NON-COVALENT BINDING THE UNIVERSITY OF TEXAS (US) 2004-10-14 WO disclosed
CN-1486985-A Synthesis of anticancer medicine Raltiprexed 首都师范大学 2004-04-07 CN disclosed
CN-1432069-A Degradable nucleic acid probes and methods for nucleic acid detection NAXCOR (US) 2003-07-23 CN disclosed
US-5780617-A PHOSPHORYLATION OF A PHOSPHATIDES WITH A NUCLEOTIDES NEXSTAR PHARMACEUTICALS, INC. (US) 1998-07-14 US disclosed
EP-0531452-A4 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES 1993-06-09 EP disclosed
EP-0531452-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES NeXstar Pharmaceuticals, Inc. (US) 1993-03-17 EP disclosed
WO-1991018914-A1 SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES VICAL, INC. (US) 1991-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179083-A1 Covalent attachment of ligands to nucleophilic proteins guided by non-covalent binding FABP1, FPR1, ADGRF1 ADRA1A 1438/4885TK1 1556/4885LMNA 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.