Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101435 | 0.89 | ADORA2B (0.41) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL8405843 | 0.80 | TNF (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL5712376 | 0.80 | SMN1; SMN2 (0.40) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL5712367 | 0.80 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL5712356 | 0.77 | MAPK1 (0.45) | KDM4EALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL8424278 | 0.75 | LMNA (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL9954457 | 0.73 | HCAR1 (0.50) | SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL9953965 | 0.73 | POLB (0.41) | MEN1KMT2ATYMSNPC1 | |
| SCHEMBL10517573 | 0.72 | NPC1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL9954005 | 0.72 | HCAR1 (0.40) | ALDH1A1SMN1; SMN2LMNATYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344775-B1 | Preparation of fungicidal quinazolinones and useful intermediates | DU PONT (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |