Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405843 | 0.91 | TNF (0.43) | ADORA2BTNFSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5712366 | 0.89 | KDM4E (0.40) | TNFSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8424278 | 0.84 | LMNA (0.43) | ADORA2BSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL31240990 | 0.83 | CACNA2D1 (0.47) | ADORA2BMEN1KMT2A | |
| SCHEMBL5712361 | 0.81 | ADORA2B (0.40) | ADORA2BSMN1; SMN2ALDH1A1ADORA2A | |
| SCHEMBL7100456 | 0.81 | DHFR (0.43) | SMN1; SMN2KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL5712376 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL5712394 | 0.80 | MTNR1A (0.40) | ADORA2BSMN1; SMN2ALDH1A1ADORA2A | |
| SCHEMBL8401780 | 0.80 | DHFR (0.43) | SMN1; SMN2KDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL5712377 | 0.80 | ALDH1A1 (0.52) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | claimed |
| US-6166208-A | Preparation of fungicidal quinazolinones and useful intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-26 | — | — | US | claimed |
| EP-0922037-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1997048684-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-24 | — | — | WO | claimed |
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6166208-A | Preparation of fungicidal quinazolinones and useful intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0946095-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0922037-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998026664-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |
| WO-1997048684-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |