Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100456 | 0.89 | DHFR (0.43) | ALDH1A1SMN1; SMN2DHFRKDM4ELMNA | |
| SCHEMBL8401780 | 0.88 | DHFR (0.43) | ALDH1A1SMN1; SMN2DHFRKDM4ELMNA | |
| SCHEMBL8401779 | 0.87 | DHFR (0.42) | ALDH1A1SMN1; SMN2DHFRKDM4ELMNA | |
| SCHEMBL5712366 | 0.80 | KDM4E (0.40) | ALDH1A1MAPK1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5712377 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL5712356 | 0.75 | MAPK1 (0.45) | ALDH1A1MAPK1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7887739 | 0.73 | PDE7A (0.53) | ALDH1A1DHFR | |
| SCHEMBL7101435 | 0.72 | ADORA2B (0.41) | ALDH1A1SMN1; SMN2RAB9AKDM4EMEN1 | |
| SCHEMBL11675393 | 0.71 | CA12 (0.54) | ALDH1A1SMN1; SMN2DHFRKDM4E | |
| SCHEMBL8424278 | 0.70 | LMNA (0.43) | ALDH1A1SMN1; SMN2RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344775-B1 | Preparation of fungicidal quinazolinones and useful intermediates | DU PONT (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |