Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.54 |
| ▸ | CTSB | P07858 | 5/20 | 0.52 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259821 | 0.94 | PSMB1 (0.49) | CAPN1CTSBMMP1MMP3MMP9 | |
| SCHEMBL6465336 | 0.94 | PSMB1 (0.49) | CAPN1CTSBMMP1MMP3MMP9 | |
| SCHEMBL30450002 | 0.94 | PSMB1 (0.49) | CAPN1CTSBMMP1MMP3MMP9 | |
| SCHEMBL5712422 | 0.93 | CTSB (0.61) | CAPN1CTSBMMP1MMP3PSMB1 | |
| Carbamic Acid SCHEMBL30450803 | 0.91 | CAPN1 (0.48) | CAPN1CTSBMMP1MMP3CTSL | |
| SCHEMBL4968073 | 0.82 | MME (0.59) | MMP1MMP3MEN1KMT2AMMP2 | |
| SCHEMBL17653337 | 0.76 | MEN1 (0.51) | MMP1MMP3MEN1KMT2AMMP2 | |
| SCHEMBL20603581 | 0.75 | PSMB5 (0.50) | MMP1MMP3MMP2MMP7MMP9 | |
| SCHEMBL20741008 | 0.75 | CTSK (0.48) | MMP1MMP3MMP2MMP7MMP9 | |
| SCHEMBL20741006 | 0.75 | CTSK (0.48) | MMP1MMP3MMP2MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337269-B1 | ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS | SOD CONSEILS RECH APPLIC (FR) | 2006-11-08 | — | — | EP | claimed |