SCHEMBL30450002

SCHEMBL30450002

CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N(Cc1ccccc1)C(=O)O.CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N(Cc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PSMB1 P20618 2/20 0.49
PSMB5 P28074 2/20 0.49
PSMB2 P49721 2/20 0.49
CAPN1 P07384 2/20 0.49
CTSB P07858 2/20 0.47
CTSL P07711 2/20 0.45
CMA1 P23946 1/20 0.43
CTRC Q99895 1/20 0.43
MMP1 P03956 1/20 0.43
MMP3 P08254 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MME P08473 1/20 0.43
ANPEP P15144 1/20 0.43
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP14 P50281 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25259821 1.00 PSMB1 (0.49) PSMB1PSMB5PSMB2CAPN1CTSB
SCHEMBL6465336 1.00 PSMB1 (0.49) PSMB1PSMB5PSMB2CAPN1CTSB
Carbamic Acid SCHEMBL30450803 0.97 CAPN1 (0.48) PSMB1PSMB5PSMB2CAPN1CTSB
SCHEMBL5712419 0.94 CAPN1 (0.54) PSMB1PSMB5PSMB2CAPN1CTSB
SCHEMBL5712422 0.87 CTSB (0.61) PSMB1PSMB5PSMB2CAPN1CTSB
SCHEMBL4968073 0.85 MME (0.59) CTSLMMP1MMP3MMEMMP9
SCHEMBL3362027 0.81 CAPN1 (0.46) PSMB1PSMB5PSMB2CAPN1CTSB
SCHEMBL2246262 0.81 MME (0.47) PSMB1PSMB5PSMB2CTSLMMP1
SCHEMBL3368130 0.81 ALDH1A1 (0.43) PSMB1PSMB5PSMB2CTSLMMP1
SCHEMBL20741008 0.80 CTSK (0.48) CTSLMMP1MMP3ALDH1A1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023101457-A1 COMPOSITION FOR PREVENTING OR TREATING BILIARY TRACT CANCER 연세대학교 산학협력단 2023-06-08 WO disclosed