Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712419 | 0.93 | CAPN1 (0.54) | CTSBCAPN1MMP1MMP3PSMB1 | |
| SCHEMBL25259821 | 0.87 | PSMB1 (0.49) | CTSBCAPN1MMP1MMP3PSMB1 | |
| SCHEMBL30450002 | 0.87 | PSMB1 (0.49) | CTSBCAPN1MMP1MMP3PSMB1 | |
| SCHEMBL6465336 | 0.87 | PSMB1 (0.49) | CTSBCAPN1MMP1MMP3PSMB1 | |
| Carbamic Acid SCHEMBL30450803 | 0.85 | CAPN1 (0.48) | CTSBCAPN1MMP1MMP3PSMB1 | |
| SCHEMBL4968073 | 0.80 | MME (0.59) | MMP1MMP3 | |
| SCHEMBL8260887 | 0.79 | CTSB (0.65) | CTSBCAPN1CTSK | |
| SCHEMBL3487670 | 0.79 | CTSB (0.65) | CTSBCAPN1CTSK | |
| SCHEMBL20603581 | 0.78 | PSMB5 (0.50) | MMP1MMP3PSMB1PSMB5PSMB2 | |
| SCHEMBL5572956 | 0.78 | CTSB (0.63) | CTSBPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337269-B1 | ASSOCIATION OF CALPAIN INHIBITORS AND REACTIVE OXYGEN SPECIES TRAPPING AGENTS | SOD CONSEILS RECH APPLIC (FR) | 2006-11-08 | — | — | EP | claimed |