Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505956 | 0.85 | PYGM (0.56) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL6529413 | 0.84 | LMNA (0.58) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL6500040 | 0.83 | KDM4E (0.60) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL6503393 | 0.82 | HSD17B10 (0.62) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL5551592 | 0.81 | LMNA (0.62) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL6529824 | 0.81 | LMNA (0.62) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL5717623 | 0.80 | ALDH1A1 (0.67) | CASP1CASP7HSD17B10LMNAMAPT | |
| SCHEMBL6497804 | 0.80 | KDM4E (0.64) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| SCHEMBL8861179 | 0.79 | ALDH1A1 (0.70) | CASP1CASP7HSD17B10L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8011144 | 0.77 | LMNA (0.71) | CASP1CASP7HSD17B10L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005021547-A2 | HETEROCYCLIC CANNABINOID CB2 RECEPTOR ANTAGONISTS | PHARMAXIS PTY LTD. (AU) | 2005-03-10 | — | — | WO | disclosed |