Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.32 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718183 | 0.93 | KMT2A (0.33) | HSD17B10ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5717924 | 0.91 | LMNA (0.37) | HSD17B10ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5722487 | 0.90 | ALDH1A1 (0.35) | HSD17B10ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5717908 | 0.90 | ALDH1A1 (0.35) | HSD17B10ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5722493 | 0.90 | SENP5 (0.35) | ALDH1A1GAAKDM4EKMT2APKM | |
| SCHEMBL5717907 | 0.90 | MAPT (0.35) | HSD17B10ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5717845 | 0.88 | MRGPRX4 (0.38) | MRGPRX4 | |
| SCHEMBL5718006 | 0.88 | PLAU (0.40) | ALDH1A1KMT2APKMPLAULMNA | |
| SCHEMBL5722638 | 0.88 | MAPK1 (0.37) | HSD17B10ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL5717816 | 0.87 | THRA (0.36) | HSD17B10ALDH1A1GAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732533-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092317-A1 | THYROID RECEPTOR AGONISTS | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |