Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5720591 | 0.98 | APOBEC3A (0.50) | APOBEC3AAPOBEC3GALDH1A1MAPK1RAD52 | |
| SCHEMBL19153815 | 0.76 | DPP4 (0.32) | — | |
| SCHEMBL8132842 | 0.76 | APOBEC3A (0.52) | APOBEC3AAPOBEC3GALDH1A1MAPK1RAD52 | |
| SCHEMBL18237620 | 0.72 | GRM5 (0.33) | MAPK1RAD52RECQLGAARAB9A | |
| SCHEMBL19131904 | 0.72 | GRM5 (0.33) | — | |
| SCHEMBL624175 | 0.70 | — | — | |
| SCHEMBL558522 | 0.70 | APOBEC3A (0.95) | APOBEC3AAPOBEC3GALDH1A1MAPK1RAD52 | |
| SCHEMBL27034730 | 0.68 | APOBEC3A (0.43) | APOBEC3AAPOBEC3GALDH1A1MAPK1RAD52 | |
| Iodide SCHEMBL4937558 | 0.68 | APOBEC3A (0.91) | APOBEC3AAPOBEC3GALDH1A1MAPK1RAD52 | |
| Hydrochloric Acid SCHEMBL963094 | 0.68 | APOBEC3A (0.83) | APOBEC3AAPOBEC3GALDH1A1MAPK1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178304-B | Synthesis method of pramipexole dihydrochloride | 中国药科大学 | 2024-10-25 | — | — | CN | claimed |
| CN-118239904-A | Chiral synthesis method of 2, 6-diamino-4, 5,6, 7-tetrahydrobenzothiazole optical isomer | 福建福瑞明德药业有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-116694585-A | Application of ketoamine reductase in synthesizing chiral pramipexole and synthetic method | 华侨大学 | 2023-09-05 | — | — | CN | claimed |
| CN-116178304-A | Synthesis method of pramipexole dihydrochloride | 中国药科大学 | 2023-05-30 | — | — | CN | claimed |
| EP-1318986-B1 | PROCESS FOR PREPARATION OF 2-AMINO-6-(ALKYL) AMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLES | SYNTHON BV (NL) | 2006-05-31 | — | — | EP | claimed |
| US-6770761-B2 | BROMINATION OF 1,4-CYCLOHEXANEDIONE BY BROMINE IN AN ALCOHOLIC SOLVENT; TREATMENT WITH THIOUREA OR N-ACYLTHIOUREA; ISOMERIZATION, CYCLIZATION; PRAMIPEXOLE SYNTHESIS | SYNTHON BV (NL) | 2004-08-03 | — | — | US | claimed |
| US-20040029936-A1 | Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles | SYNTHON IP INC. | 2004-02-12 | — | — | US | claimed |
| EP-1318986-A1 | PROCESS FOR PREPARATION OF 2-AMINO-6-(ALKYL) AMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLES | Synthon B.V. (NL) | 2003-06-18 | — | — | EP | claimed |
| WO-2002022590-A1 | PROCESS FOR PREPARATION OF 2-AMINO-6-(ALKYL) AMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLES | SYNTHON B.V. (NL) | 2002-03-21 | — | — | WO | claimed |
| CN-118239904-B | Chiral synthesis method of 2, 6-diamino-4, 5,6, 7-tetrahydrobenzothiazole optical isomer | 福建福瑞明德药业有限公司 | 2025-10-17 | — | — | CN | disclosed |
| EP-4558494-A1 | 1,3,4-OXADIAZOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | ITALFARMACO S.p.A. (IT) | 2025-05-28 | — | — | EP | disclosed |
| CN-119562949-A | 1,3, 4-Oxadiazole derivatives as selective histone deacetylase 6 inhibitors | 意大发马克股份公司 | 2025-03-04 | — | — | CN | disclosed |
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-31 | — | — | US | disclosed |
| CN-116178304-B | Synthesis method of pramipexole dihydrochloride | 中国药科大学 | 2024-10-25 | — | — | CN | disclosed |
| US-20040029936-A1 | Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles | SYNTHON IP INC. | 2004-02-12 | — | — | US | disclosed |
| EP-1318986-A1 | PROCESS FOR PREPARATION OF 2-AMINO-6-(ALKYL) AMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLES | Synthon B.V. (NL) | 2003-06-18 | — | — | EP | disclosed |
| EP-1318987-A1 | PROCESS FOR RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLE AND COMPOUNDS THEREFOR | Synthon B.V. (NL) | 2003-06-18 | — | — | EP | disclosed |
| US-20020103240-A1 | Process for resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole and compounds therefor | SYNTHON IP INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2002022591-A1 | PROCESS FOR RESOLUTION OF 2-AMINO-6-PROPYLAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLE AND COMPOUNDS THEREFOR | SYNTHON B.V. (NL) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022590-A1 | PROCESS FOR PREPARATION OF 2-AMINO-6-(ALKYL) AMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLES | SYNTHON B.V. (NL) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103240-A1 | Process for resolution of 2-amino-6-propylamino-4,5,6,7-tetrahydrobenzthiazole and compounds therefor | NOTUM, SLC5A6, WEE2 | APOBEC3A 4792/4885APOBEC3G 4669/4885ALDH1A1 3519/4885 |
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | APOBEC3A 4192/4885APOBEC3G 3833/4885ALDH1A1 1441/4885 |
| US-20040029936-A1 | Process for preparation of 2-amino-6 (alkyl) amino-4,5,6,7-tetrahydrobenzothiazoles | PAH, HTR6, HTR4 | APOBEC3A 3850/4885APOBEC3G 3502/4885ALDH1A1 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.