Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.32 |
| ▸ | C1S | P09871 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1467918 | 0.79 | F2 (0.44) | F2F10F12F7F3 | |
| SCHEMBL5846504 | 0.77 | CES2 (0.41) | F2F10F12F7F3 | |
| SCHEMBL10495291 | 0.76 | ALDH1A1 (0.41) | F2F10F12F7F3 | |
| SCHEMBL458997 | 0.76 | F2 (0.41) | F2F10F12F7F3 | |
| SCHEMBL10495281 | 0.70 | F2 (0.55) | F2F10F12F7F3 | |
| SCHEMBL28513902 | 0.69 | BCAT2 (0.50) | F2F10F12F7F3 | |
| SCHEMBL8988809 | 0.69 | GAA (0.38) | F2F10F12F7F3 | |
| SCHEMBL7083509 | 0.68 | CYP2C19 (0.38) | F2F10F12F7F3 | |
| Hydrochloric Acid SCHEMBL28555632 | 0.68 | BLM (0.57) | F2F10F12F7F3 | |
| Hydrochloric Acid SCHEMBL29008442 | 0.68 | BLM (0.57) | F2F10F12F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131315-B1 | POLYHYDROXYLATED HETEROCYCLIC DERIVATIVES AS ANTI-COAGULANTS | BERLEX LAB (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-0934310-B1 | THIO ACID DERIVED MONOCYCLIC N-HETEROCYCLICS AS ANTICOAGULANTS | SCHERING AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| EP-0888271-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LAB (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-1040108-B1 | ORTHO-ANTHRANILAMIDE DERIVATIVES AS ANTI-COAGULANTS | SCHERING AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-0813525-B9 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LAB (US) | 2004-02-04 | — | — | EP | disclosed |
| US-6686367-B2 | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants | BERLEX LABORATORIES, INC. | 2004-02-03 | — | — | US | disclosed |
| US-6686364-B2 | 4-HYDROXY-3-((3,5-DIFLUORO-6-(3 -DIMETHYLAMINOCARBONYLPHENOXY)-4-(2-METHOXY-4-CARBOXYPHENOXY) PYRIDIN-2-YL)OXY)BENZAMIDINE, FOR EXAMPLE; FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. | 2004-02-03 | — | — | US | disclosed |
| EP-0813525-B1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LAB (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-0920430-B1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2003-09-24 | — | — | EP | disclosed |
| US-20030149040-A1 | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants | BERLEX LABORATORIES, INC. | 2003-08-07 | — | — | US | disclosed |
| US-5726173-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1998007723-A1 | BICYCLIC PYRIMIDINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |
| EP-0813525-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5693641-A | ENZYME INHIBITOR TREATING BLOOD DISORDER | BERLEX LABORATORIES INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5691364-A | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. (US) | 1997-11-25 | — | — | US | disclosed |
| WO-1997029067-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-08-14 | — | — | WO | disclosed |
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996038421-A1 | N,N-DI(ARYLMETHYL)CYCLIC UREA DERIVATIVES AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996028427-A1 | BENZAMIDINE DERIVATIVES THEIR PREPARATION AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1996-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149040-A1 | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants | F2, SERPINC1, F8 | F2 1/4885F10 9/4885F12 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.