Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.35 |
| ▸ | F2 | P00734 | 5/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593438 | 0.72 | CA1 (0.56) | PRSS1PRSS2PRSS3F2CA1 | |
| SCHEMBL7562109 | 0.72 | TTR (0.41) | GAAPRSS1PRSS2PRSS3F2 | |
| SCHEMBL4593659 | 0.72 | CDK2 (0.47) | PRSS1PRSS2PRSS3F2CA1 | |
| SCHEMBL458997 | 0.71 | F2 (0.41) | GAAPRSS1PRSS2PRSS3F2 | |
| SCHEMBL10495291 | 0.71 | ALDH1A1 (0.41) | F2PLAUCA1CA2CA9 | |
| SCHEMBL3555054 | 0.71 | BCAT2 (0.50) | PRSS1PRSS2PRSS3F2CA1 | |
| SCHEMBL5740371 | 0.69 | F2 (0.34) | PRSS1PRSS2PRSS3F2PLAU | |
| Guanidine SCHEMBL9460797 | 0.69 | F2 (0.59) | GAAPRSS1PRSS2PRSS3F2 | |
| Guanidine SCHEMBL9459681 | 0.69 | F2 (0.59) | GAAPRSS1PRSS2PRSS3F2 | |
| SCHEMBL29435078 | 0.68 | ALOX15 (0.48) | PRSS1PRSS2PRSS3F2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516813-A | ROTORS | STARKEY DONN R (US) | 1996-05-14 | — | — | US | disclosed |
| US-5384339-A | Quartz or silica radiation transparent filler, dynamic testing | STARKEY DONN R (US) | 1995-01-24 | — | — | US | disclosed |