Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPIB | P23284 | 1/20 | 0.37 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185264 | 0.84 | LMNA (0.41) | SMN1; SMN2GAAALDH1A1MAPTMAPK1 | |
| SCHEMBL4597795 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL5627469 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL2131830 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL17161212 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL9606724 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL11147975 | 0.79 | THRB (0.46) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL19592643 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL14676758 | 0.78 | THRA (0.42) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT | |
| SCHEMBL24207037 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP4Z1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383729-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-04-19 | — | — | EP | disclosed |
| US-20040267015-A1 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-12-30 | — | — | US | disclosed |
| EP-1383729-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002081426-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267015-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | SMN1; SMN2 2376/4885CYP4Z1 4588/4885GAA 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.