Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.57 |
| ▸ | THRA | P10827 | 15/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122041 | 0.86 | THRB (0.51) | THRBTHRARORC | |
| SCHEMBL3923780 | 0.86 | THRA (0.55) | THRBTHRAHSP90AB1LMNA | |
| SCHEMBL5740828 | 0.82 | THRB (0.57) | THRBTHRASTK39RORC | |
| SCHEMBL3914044 | 0.81 | THRA (0.50) | THRBTHRALMNA | |
| SCHEMBL5388207 | 0.81 | THRB (0.49) | THRBTHRAHSP90AB1LMNA | |
| SCHEMBL5385598 | 0.81 | THRB (0.49) | THRBTHRAHSP90AB1LMNA | |
| SCHEMBL7114974 | 0.80 | THRB (0.45) | THRBTHRARORC | |
| SCHEMBL7122312 | 0.80 | RNF4 (0.47) | THRBTHRARORC | |
| SCHEMBL12337187 | 0.80 | THRA (0.48) | THRBTHRAHSP90AB1LMNA | |
| SCHEMBL5393176 | 0.79 | THRB (0.57) | THRBTHRARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383729-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-04-19 | — | — | EP | disclosed |
| US-20040267015-A1 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-12-30 | — | — | US | disclosed |
| EP-1383729-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002081426-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267015-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | THRB 2643/4885THRA 3654/4885HSP90AB1 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.