SCHEMBL57449

SCHEMBL57449

CO[Si](C)(CNc1ccccc1)OC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
ALDH1A1 P00352 3/20 0.41
KCNH3 Q9ULD8 2/20 0.39
TAAR1 Q96RJ0 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
LTA4H P09960 1/20 0.35
NPC1 O15118 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629259 0.93 MAPT (0.38) MAPTALDH1A1KCNH3TAAR1MAOA
SCHEMBL788211 0.92 MAPT (0.40) MAPTALDH1A1KCNH3TAAR1MAOA
SCHEMBL978043 0.83 MAPT (0.42) MAPTALDH1A1KCNH3TAAR1MAOA
Benzene SCHEMBL28332770 0.81 MAPT (0.43) MAPTALDH1A1KCNH3TAAR1MAOA
SCHEMBL114143 0.81 MAPT (0.43) MAPTALDH1A1KCNH3TAAR1MAOA
SCHEMBL15360346 0.80 MAPT (0.48) MAPTALDH1A1KCNH3TAAR1MAOA
SCHEMBL774107 0.80 NPSR1 (0.39) MAPTALDH1A1KCNH3MAOAMAOB
SCHEMBL268348 0.78 ALDH1A1 (0.48) MAPTALDH1A1TAAR1MAOAMAOB
SCHEMBL22911739 0.78 MAPT (0.44) MAPTALDH1A1KCNH3TAAR1MAOA
SCHEMBL49467 0.77 MAPT (0.55) MAPTALDH1A1KCNH3L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041693-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-26 WO claimed
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP claimed
US-20260042878-A1 Curable Compositions Comprising At Least One Silane-Modified Polymer HENKEL AG & CO KGAA (DE) 2026-02-12 US claimed
WO-2025198684-A9 BaTiO3 NANOCRYSTALS AND NANOCOMPOSITES PIXELLIGENT TECHNOLOGIES LLC (US) 2025-11-27 WO claimed
EP-4638540-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA Spolka Akcyjna (PL) 2025-10-29 EP claimed
US-20250326910-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE DÄTWYLER SCHWEIZ AG (CH) 2025-10-23 US claimed
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN claimed
US-20250197703-A1 Chemical Mechanical Planarization Using Amino-Polyorganosiloxane-Coated Abrasives VERSUM MATERIALS US, LLC 2025-06-19 US claimed
WO-2025097879-A1 SINGLE-ENDED POLYFUNCTIONAL STYRENE-CONJUGATED DIENE POLYMER, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国石油天然气股份有限公司 2025-05-15 WO claimed
CN-119955037-A Double-ended siloxane-based styrene-butadiene polymer, preparation method thereof, rubber composition and vulcanized rubber 中国石油天然气股份有限公司 2025-05-09 CN claimed
CN-101381537-A Solvent-free water-soluble ink compound and preparation method thereof ZHANGJIAGANG CITY YINGLI TECHN (CN) 2009-03-11 CN claimed
EP-1735369-B1 FAST CURING POLYDIORGANOSILOXANES HENKEL AG & CO KGAA (DE) 2008-12-03 EP claimed
US-20070135601-A1 Initiator systems for polymerisable compositions HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (US) 2007-06-14 US claimed
JP-2007510788-A 2007-04-26 JP claimed
EP-1735369-A1 FAST CURING POLYDIORGANOSILOXANES Henkel Kommanditgesellschaft auf Aktien (DE) 2006-12-27 EP claimed
EP-1685165-A1 INITIATOR SYSTEMS FOR POLYMERISABLE COMPOSITIONS Huntsman Advanced Materials (Switzerland) GmbH (CH) 2006-08-02 EP claimed
WO-2005100446-A1 FAST CURING POLYDIORGANOSILOXANES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-10-27 WO claimed
US-20050234208-A1 Fast curing polydiorganosiloxanes HENKEL AG & CO. KGAA (DE) 2005-10-20 US claimed
WO-2005044867-A1 INITIATOR SYSTEMS FOR POLYMERISABLE COMPOSITIONS HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-05-19 WO claimed
US-20050101753-A1 Method of increasing the elasticity of moisture-cured elastomers WACKER-CHEMIE GMBH (DE) 2005-05-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135601-A1 Initiator systems for polymerisable compositions PFAS, PTK2, PNN MAPT 1447/4885ALDH1A1 2675/4885KCNH3 4588/4885
US-20260042878-A1 Curable Compositions Comprising At Least One Silane-Modified Polymer CDH1, MECP2, COL14A1 MAPT 1721/4885ALDH1A1 2682/4885KCNH3 1567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.