Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6578636 | 0.97 | GAA (0.33) | GAAMAPK1RXFP1THRBKDM4E | |
| SCHEMBL9822907 | 0.81 | THRB (0.31) | THRB | |
| SCHEMBL8767328 | 0.79 | GABRA2 (0.41) | GABRB3GABRA2GABRB2ALDH1A1 | |
| SCHEMBL10497056 | 0.78 | THRB (0.33) | THRBHTT | |
| SCHEMBL3326974 | 0.72 | RAPGEF3 (0.34) | GAAMAPK1RXFP1MRGPRX4ALDH1A1 | |
| SCHEMBL5746326 | 0.70 | MRGPRX4 (0.36) | KDM4EMRGPRX4HTTALDH1A1MAPT | |
| SCHEMBL11279678 | 0.70 | AR (0.41) | GAAMAPK1THRBHTTALDH1A1 | |
| SCHEMBL5795159 | 0.69 | TRPV4 (0.52) | MRGPRX4 | |
| SCHEMBL11279682 | 0.68 | THRB (0.36) | GAATHRBHTTALDH1A1 | |
| SCHEMBL5744932 | 0.68 | MRGPRX4 (0.34) | GAAMAPK1RXFP1KDM4EMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788484-A1 | 2-CHLORO-N- 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AG (DE) | 1997-08-13 | — | — | EP | claimed |
| WO-1996012707-A1 | 2-CHLORO-N-[1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-02 | — | — | WO | claimed |
| US-7094906-B2 | Processes for preparing pesticidal intermediates | Basf Agro B.V. Arnthem (NL) Wädenswil-Branch (CH) | 2006-08-22 | — | — | US | disclosed |
| EP-0952145-B1 | Process for preparing pesticidal intermediates | BASF AGRO BV (CH) | 2005-10-05 | — | — | EP | disclosed |
| EP-1073627-B1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | BAYER AGRICULTURE LTD (GB) | 2004-12-01 | — | — | EP | disclosed |
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | AVENTIS AGRICULTURE LTD. (GB) | 2004-10-07 | — | — | US | disclosed |
| CN-1158249-C | Processes for preparing pesticidal intermediates | ��������ũҵ�� | 2004-07-21 | — | — | CN | disclosed |
| US-6673956-B2 | INTERMEDIATES (PARTICULARLY 2-(ARYLHYDRAZINO)SUCCINONITRILE COMPOUNDS AND 3-(ARYLHYDRAZONO)PROPIONITRILE DERIVATIVES FOR PESTICIDES, BY REACTING DIALKOXYPROPIONITRILE WITH AN ACID ADDITION SALT OF ARYLHYDRAZINE | AVENTIS AGRICULTURE LTD. (GB) | 2004-01-06 | — | — | US | disclosed |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | MERIAL LIMITED | 2002-09-12 | — | — | US | disclosed |
| US-6392081-B1 | REACTING A NITRILE COMPOUND CONTAINING ACTAL GROUPS WITH ARYLHYDRAZINE; OXIDATION | AVENTIS AGRICULTURE LTD. (GB) | 2002-05-21 | — | — | US | disclosed |
| CN-1297429-A | Process for preparing pesticidal intermediates | AFANTI AGRICULTURE LTD (GB) | 2001-05-30 | — | — | CN | disclosed |
| EP-1073627-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 2001-02-07 | — | — | EP | disclosed |
| EP-1070748-A1 | Powder coating compositions, their preparation and use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-01-24 | — | — | EP | disclosed |
| US-6114489-A | POWDER COATING COMPOSITIONS CONTAINING NOVEL ALIPHATIC HYPERBRANCHED POLYESTER POLYMERS, WHICH FUNCTION EITHER AS POLYMERIC CROSSLINKERS OR AS FLOW AND LEVELING AGENTS | HERBERTS GMBH (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999054288-A1 | PROCESSES FOR PREPARING PESTICIDAL INTERMEDIATES | AVENTIS AGRICULTURE LTD. (GB) | 1999-10-28 | — | — | WO | disclosed |
| EP-0952145-A1 | Process for preparing pesticidal intermediates | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-10-27 | — | — | EP | disclosed |
| EP-0788484-A1 | 2-CHLORO-N- 1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996012707-A1 | 2-CHLORO-N-[1-(2,6-DICHLORO-4-DIFLUOROMETHYL-PHENYL)-1H-PYRAZOL-5-YL]-PROPANAMIDE AND A METHOD OF PRODUCING THE SAME | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-02 | — | — | WO | disclosed |
| EP-0303153-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1989-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198985-A1 | Processes for preparing pesticidal intermediates | SFXN3, SFXN1, CYP4F3 | GAA 4661/4885MAPK1 2497/4885RXFP1 1869/4885 |
| US-20020128485-A1 | Processes for preparing pesticidal intermediates | CBR3, HCN1, SF3A3 | GAA 4790/4885MAPK1 1992/4885RXFP1 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.