Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24254460 | 0.72 | GAA (0.56) | ALDH1A1GAAHSD17B10CES2CES1 | |
| SCHEMBL11716133 | 0.71 | ALDH1A1 (0.49) | ALDH1A1GAAHSD17B10HTTCES2 | |
| SCHEMBL135362 | 0.71 | ELANE (0.60) | ALDH1A1ALOX15ELANEF2PLAU | |
| SCHEMBL289609 | 0.70 | GAA (0.50) | ALDH1A1GAAHSD17B10CES2CES1 | |
| SCHEMBL15752416 | 0.69 | ELANE (0.60) | ALDH1A1ALOX15ELANEGAAHSD17B10 | |
| SCHEMBL11293119 | 0.68 | GAA (0.85) | ALDH1A1ALOX15GAAHSD17B10HTT | |
| SCHEMBL1656261 | 0.68 | HCAR2 (0.43) | ALDH1A1GAAHSD17B10HTTCES2 | |
| SCHEMBL6270074 | 0.67 | L3MBTL1 (0.56) | ALDH1A1ALOX15ELANECES2CES1 | |
| SCHEMBL11848471 | 0.67 | ELANE (0.59) | ALDH1A1ALOX15ELANEHPGDHTT | |
| SCHEMBL1066873 | 0.66 | CES2 (1.00) | ALDH1A1ALOX15GAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | claimed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | claimed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | disclosed |
| EP-4196108-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | The Trustees of Indiana University (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022036282-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2006069767-A1 | PROCESS FOR OBTAINING ENANTIOMERS OF THIENYLAZOLYLALCOXYETHANAMINES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-07-06 | — | — | WO | disclosed |
| EP-1674465-A1 | Process for obtaining enantiomers of thienylazolylalcoxyethanamines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-06-28 | — | — | EP | disclosed |
| US-6979742-B1 | Process for obtaining enantiomers of thienylazolylalcoxyethanamines | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | PGLS, BLVRB, CGAS | ALDH1A1 4358/4885ALOX15 737/4885ELANE 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.