Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728503 | 0.77 | ADRA2A (0.52) | MAPTL3MBTL1MAPK1ALDH1A1MEN1 | |
| SCHEMBL9728352 | 0.70 | SMN1; SMN2 (0.40) | MAPTALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL574986 | 0.68 | NPSR1 (0.38) | MAPTMAPK1ALDH1A1KDM4ECHRNA7 | |
| SCHEMBL9728419 | 0.68 | L3MBTL1 (0.43) | TDP1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9728461 | 0.60 | TDP1 (0.35) | TDP1 | |
| SCHEMBL28644499 | 0.59 | ALDH1A1 (0.49) | TDP1MAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL7375304 | 0.59 | ADRB1 (0.40) | TDP1MAPTL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL474882 | 0.57 | SIGMAR1 (0.52) | MAPTL3MBTL1MAPK1ALDH1A1CHRNA7 | |
| SCHEMBL30277734 | 0.56 | ALDH1A1 (0.58) | TDP1MAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL13416394 | 0.56 | KMT2A (0.51) | MAPTL3MBTL1MAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098926-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4888341-A | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-12-19 | — | — | US | disclosed |