Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728456 | 0.70 | TDP1 (0.35) | MAPTKDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL9728503 | 0.70 | ADRA2A (0.52) | MAPTTSHRALDH1A1LMNA | |
| SCHEMBL574986 | 0.69 | NPSR1 (0.38) | SMN1; SMN2MAPTKDM4ETSHRALDH1A1 | |
| SCHEMBL9728419 | 0.69 | L3MBTL1 (0.43) | SMN1; SMN2MAPTKDM4ETSHRALDH1A1 | |
| SCHEMBL11577567 | 0.68 | KCNH2 (0.62) | MAPTKDM4EALDH1A1POLBKCNA3 | |
| SCHEMBL28844443 | 0.63 | SIGMAR1 (0.37) | SMN1; SMN2TSHRALDH1A1KCNA3LMNA | |
| SCHEMBL1307855 | 0.60 | CHRNA7 (0.58) | MAPTKDM4EALDH1A1POLBKCNA3 | |
| SCHEMBL9728348 | 0.59 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTKDM4ETSHRCYP1A2 | |
| SCHEMBL474882 | 0.58 | SIGMAR1 (0.52) | SMN1; SMN2MAPTTSHRALDH1A1POLB | |
| SCHEMBL11713164 | 0.57 | NPSR1 (0.49) | SMN1; SMN2MAPTKDM4ETSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098926-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4888341-A | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-12-19 | — | — | US | disclosed |