Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | TDO2 | P48775 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282007 | 0.94 | XDH (0.37) | XDHTTRLMNA | |
| SCHEMBL3117809 | 0.81 | ALOX15 (0.46) | TTRKDM4EHPGDALOX15NFKB1 | |
| SCHEMBL17130065 | 0.73 | XDH (0.57) | XDHKDM4EALDH1A1 | |
| SCHEMBL402033 | 0.70 | ALDH1A1 (0.50) | KDM4EHPGDALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL5889599 | 0.69 | MMP1 (0.39) | KDM4E | |
| SCHEMBL23421678 | 0.69 | HRH3 (0.46) | KDM4EHPGDALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL27925124 | 0.68 | POLB (0.46) | HPGDLMNATPMT | |
| SCHEMBL8444440 | 0.67 | NFKB1 (0.46) | EIF4A3IDO1TDO2KDM4EHPGD | |
| SCHEMBL17999890 | 0.67 | MAP2K1 (0.41) | XDHTTRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5889521 | 0.67 | HRH3 (0.64) | XDHKDM4EHPGDNFKB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664025-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026149-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |