Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755208 | 0.86 | CACNA1B (0.36) | MAPTALDH1A1CTSLCTSSKDM4E | |
| SCHEMBL5754339 | 0.86 | ALDH1A1 (0.35) | ALDH1A1HPGDKMT2A | |
| SCHEMBL5752525 | 0.86 | BACE1 (0.32) | MAPTALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL5757143 | 0.86 | ALDH1A1 (0.35) | ALDH1A1HPGDKMT2A | |
| SCHEMBL5753443 | 0.85 | GSK3B (0.33) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL5756531 | 0.84 | HTR2C (0.40) | — | |
| SCHEMBL5756949 | 0.83 | REN (0.37) | RENCTSLCTSSCTSKKDM4E | |
| SCHEMBL5758658 | 0.83 | CCR1 (0.34) | TSHRALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL5753832 | 0.81 | CACNA1B (0.36) | CTSSCTSCBACE1 | |
| SCHEMBL5753219 | 0.81 | ALDH1A1 (0.34) | ALDH1A1LMNAHPGDBACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |