Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754943 | 1.00 | MEN1 (0.31) | MEN1GAAKMT2ALMNAMAPT | |
| SCHEMBL5757162 | 0.90 | CACNA1B (0.34) | KMT2A | |
| SCHEMBL5756478 | 0.90 | CACNA1B (0.34) | KMT2A | |
| SCHEMBL5755092 | 0.88 | EPHX1 (0.32) | GAALMNAMAPTL3MBTL1 | |
| SCHEMBL5755360 | 0.87 | LMNA (0.34) | MEN1GAAKMT2ALMNAMAPT | |
| SCHEMBL5752525 | 0.86 | BACE1 (0.32) | LMNAMAPTMAPK1L3MBTL1TDP1 | |
| SCHEMBL5756667 | 0.82 | REN (0.38) | KMT2A | |
| SCHEMBL5754504 | 0.81 | ACKR3 (0.32) | MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5753219 | 0.80 | ALDH1A1 (0.34) | KMT2ALMNA | |
| SCHEMBL5756787 | 0.79 | ALDH1A1 (0.34) | MEN1GAAKMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |