Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 12/20 | 0.48 |
| ▸ | FABP3 | P05413 | 3/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848072 | 0.87 | NPC1 (0.41) | FABP4FABP3FABP5NPC1RAB9A | |
| SCHEMBL15492789 | 0.78 | ACMSD (0.38) | FABP4THRBCNR2GPR35 | |
| SCHEMBL4684053 | 0.75 | FABP4 (0.48) | FABP4FABP3FABP5NPC1RAB9A | |
| SCHEMBL4572102 | 0.74 | THRB (0.45) | THRBGPR35 | |
| SCHEMBL1009517 | 0.74 | THRB (0.65) | THRBGPR35 | |
| SCHEMBL13766303 | 0.74 | FABP4 (0.38) | FABP4NPC1RAB9AERN1 | |
| SCHEMBL10070477 | 0.73 | THRB (0.39) | FABP4FABP3FABP5THRBGPR35 | |
| SCHEMBL7831457 | 0.73 | CTNNB1 (0.55) | FABP4FABP3FABP5NPC1RAB9A | |
| SCHEMBL4037029 | 0.72 | FABP4 (0.40) | FABP4FABP3FABP5NPC1RAB9A | |
| SCHEMBL2018471 | 0.71 | FABP3 (0.47) | FABP4FABP3FABP5THRBERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446406-B1 | PHOTOCHROMIC NAPHTHOPYRANS FOR OPHTHALMIC ARTICLES | VISION EASE LENS INC (US) | 2006-03-29 | — | — | EP | disclosed |
| US-7008568-B2 | Photochromic naphthopyran compounds: compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. (US) | 2006-03-07 | — | — | US | disclosed |
| EP-1446406-A2 | PHOTOCHROMIC NAPHTHOPYRANS FOR OPHTHALMIC ARTICLES | Vision-Ease Lens, Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| US-20030146419-A1 | Photochromic naphthopyran compounds: compositions and articles containing those naphthopyran compounds | VISION-EASE LENS, INC. | 2003-08-07 | — | — | US | disclosed |
| WO-2003044022-A2 | PHOTOCHROMIC NAPHTHOPYRAN FOR OPHTHALMIC ARTICLES | VISION-EASE LENS, INC. (US) | 2003-05-30 | — | — | WO | disclosed |