Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.41 |
| ▸ | HNF4A | P41235 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15452334 | 0.92 | HNF4A (0.41) | THRBGPR35POLBMCL1ACMSD | |
| SCHEMBL15459720 | 0.89 | MCL1 (0.49) | THRBGPR35POLBMCL1ACMSD | |
| SCHEMBL2018471 | 0.79 | FABP3 (0.47) | THRBGPR35POLBMCL1ACMSD | |
| SCHEMBL1009517 | 0.79 | THRB (0.65) | THRBGPR35POLBMCL1ACMSD | |
| SCHEMBL17736804 | 0.78 | ALDH1A1 (0.54) | THRBGPR35MCL1ACMSDHNF4A | |
| SCHEMBL1010666 | 0.77 | ACMSD (0.46) | THRBMCL1ACMSDHNF4ADHFR | |
| SCHEMBL9900350 | 0.76 | THRB (0.61) | THRBGPR35POLBMCL1ACMSD | |
| SCHEMBL10137154 | 0.76 | PTPN11 (0.44) | THRBPTPN1 | |
| SCHEMBL4568718 | 0.75 | GPR35 (0.33) | GPR35POLBHTT | |
| SCHEMBL15906524 | 0.75 | FABP4 (0.39) | THRBPOLBMCL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8308996-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20120121934-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121934-A1 | CHROMENE COMPOUND | TST, CNOT1, CNOT9 | THRB 2364/4885GPR35 3753/4885POLB 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.