Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA6 | P23280 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751215 | 0.79 | KDM4E (0.38) | TRPV4ADORA2AADORA1PDE4APDE4B | |
| SCHEMBL31432600 | 0.76 | TRPV4 (0.37) | CA2CA4TRPV4TP53KDM4E | |
| SCHEMBL31432595 | 0.75 | EPAS1 (0.40) | ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL1629238 | 0.75 | TRPV4 (0.39) | TRPV4KDM4ECYP3A4MAPT | |
| SCHEMBL31511101 | 0.74 | TRPV4 (0.38) | CA2CA4TRPV4ADORA2AADORA1 | |
| SCHEMBL5754985 | 0.73 | ALDH1A1 (0.42) | KDM4EBRD4CYP3A4MAPT | |
| SCHEMBL31432586 | 0.72 | CA2 (0.41) | CA2CA4TRPV4KDM4E | |
| SCHEMBL31432614 | 0.72 | TRPV4 (0.34) | CA1CA2CA4CA6TRPV4 | |
| SCHEMBL14720070 | 0.71 | ALOX5AP (0.36) | CA2CA4TRPV4ADORA2AADORA1 | |
| SCHEMBL17992 | 0.71 | TRPV4 (0.42) | TRPV4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1387839-B1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LTD (GB) | 2006-03-08 | — | — | EP | disclosed |
| US-6734303-B2 | THERAPY FOR BENIGN PROSTATIC HYPERPLASIA | PFIZER INC. | 2004-05-11 | — | — | US | disclosed |
| EP-1387839-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | Pfizer Limited (GB) | 2004-02-11 | — | — | EP | disclosed |
| US-20030004339-A1 | Process for the production of quinazolines | PFIZER INC. | 2003-01-02 | — | — | US | disclosed |
| WO-2002094815-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LIMITED (GB) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004339-A1 | Process for the production of quinazolines | BPHL, KLK3, AQP3 | CA1 2409/4885CA2 282/4885CA4 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.