Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.42 |
| ▸ | TUBB | P07437 | 2/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5753766 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL21808044 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL11563862 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL6764895 | 0.77 | ADORA2A (0.46) | ALDH1A1MAPTHSD17B10TUBB4ATUBB | |
| SCHEMBL17241240 | 0.77 | GPR35 (0.44) | ALDH1A1MAPTGAALMNAMAPK1 | |
| SCHEMBL31716918 | 0.77 | GPR35 (0.50) | ALDH1A1MAPTCYP3A4TUBB4ATUBB | |
| SCHEMBL6950804 | 0.76 | MAPK8 (0.40) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7371195 | 0.75 | VCAM1 (0.54) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL6943425 | 0.75 | TUBB4A (0.39) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL6772390 | 0.75 | ABCB1 (0.42) | ALDH1A1MAPTKDM4ETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1387839-B1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LTD (GB) | 2006-03-08 | — | — | EP | disclosed |
| US-6734303-B2 | THERAPY FOR BENIGN PROSTATIC HYPERPLASIA | PFIZER INC. | 2004-05-11 | — | — | US | disclosed |
| EP-1387839-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | Pfizer Limited (GB) | 2004-02-11 | — | — | EP | disclosed |
| US-20030004339-A1 | Process for the production of quinazolines | PFIZER INC. | 2003-01-02 | — | — | US | disclosed |
| WO-2002094815-A1 | PROCESS FOR THE PRODUCTION OF QUINAZOLINES | PFIZER LIMITED (GB) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004339-A1 | Process for the production of quinazolines | BPHL, KLK3, AQP3 | ALDH1A1 1322/4885MAPT 761/4885KDM4E 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.