Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759013 | 0.84 | GRN (0.36) | P2RX7ACACB | |
| SCHEMBL5754780 | 0.83 | CACNA1B (0.43) | P2RX7KMT2ACACNA1BACACBMEN1 | |
| SCHEMBL5755208 | 0.81 | CACNA1B (0.36) | CACNA1B | |
| SCHEMBL5756531 | 0.77 | HTR2C (0.40) | — | |
| SCHEMBL5753832 | 0.76 | CACNA1B (0.36) | CACNA1B | |
| SCHEMBL5754339 | 0.76 | ALDH1A1 (0.35) | P2RX7KMT2ACACNA1B | |
| SCHEMBL5757143 | 0.76 | ALDH1A1 (0.35) | P2RX7KMT2ACACNA1B | |
| SCHEMBL5758658 | 0.75 | CCR1 (0.34) | — | |
| SCHEMBL5754552 | 0.75 | NPC1 (0.32) | — | |
| SCHEMBL5752525 | 0.73 | BACE1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |