Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758658 | 0.91 | CCR1 (0.34) | NPC1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5757640 | 0.82 | HSD17B10 (0.40) | KDM4E | |
| SCHEMBL5752071 | 0.82 | ACHE (0.37) | NPC1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5754339 | 0.79 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL5752525 | 0.79 | BACE1 (0.32) | NPC1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5757143 | 0.79 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL5754373 | 0.78 | MAPT (0.32) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL5755208 | 0.77 | CACNA1B (0.36) | NPC1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5753443 | 0.77 | GSK3B (0.33) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL5756531 | 0.76 | HTR2C (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |