Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754552 | 0.91 | NPC1 (0.32) | KDM4ENPC1ALDH1A1LMNAHPGD | |
| SCHEMBL5754373 | 0.83 | MAPT (0.32) | SMN1; SMN2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5755652 | 0.81 | GPR119 (0.38) | CHRM4 | |
| SCHEMBL5755208 | 0.78 | CACNA1B (0.36) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL5757143 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL5752525 | 0.76 | BACE1 (0.32) | KDM4ENPC1ALDH1A1LMNAHPGD | |
| SCHEMBL5754339 | 0.76 | ALDH1A1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL5756531 | 0.76 | HTR2C (0.40) | — | |
| SCHEMBL5753443 | 0.76 | GSK3B (0.33) | KDM4EALDH1A1LMNAHTT | |
| SCHEMBL5757946 | 0.75 | P2RX7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |