Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649335 | 0.86 | MEN1 (0.64) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL1437123 | 0.86 | SLC22A6 (0.68) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL19519009 | 0.86 | PDE4D (0.60) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL4151619 | 0.85 | CYP1A2 (0.66) | MEN1KMT2ACYP1A2PLK1KDM4E | |
| SCHEMBL28325208 | 0.85 | MEN1 (0.62) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| Hydrochloric Acid SCHEMBL28155688 | 0.84 | SLC22A6 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL2086007 | 0.84 | MEN1 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL2664428 | 0.84 | MEN1 (0.66) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL16076892 | 0.83 | FYN (0.52) | MEN1KMT2ASLC22A6SLC22A8RAB9A | |
| SCHEMBL9103250 | 0.82 | TAS1R3 (0.56) | MEN1KMT2AHTTCYP1A2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245367-A1 | INHIBITING CATECHOL-O-METHYLTRANSFERASE (COMT) | PSY THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| US-20210371413-A1 | POLYCYCLIC AMIDES AS CYTOTOXIC AGENTS | Pheon Therapeutics Ltd. (GB) | 2021-12-02 | — | — | US | disclosed |
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |
| US-20160032047-A1 | Peg-based adhesive phenylic derivatives and methods of synthesis and use | DSM IP ASSETS B.V. (NL) | 2016-02-04 | — | — | US | disclosed |
| US-8962600-B2 | Neuroprotective compounds and their use | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20120329755-A1 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | GLYCOMIMETICS, INC. (US) | 2012-12-27 | — | — | US | disclosed |
| US-8258290-B2 | Glycomimetic inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from pseudomonas | GLYCOMIMETICS, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20100041626-A1 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | GLYCOMIMETICS, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| WO-2007021721-A2 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | GLYCOMIMETICS, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| EP-1663234-A1 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF HIV INFECTIONS | Pfizer Limited (GB) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005121094-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES AS ANTI-HIV-AGENTS | PFIZER LIMITED (GB) | 2005-12-22 | — | — | WO | disclosed |
| US-20050043300-A1 | Piperazine derivatives | PFIZER INC. | 2005-02-24 | — | — | US | disclosed |
| WO-2005016344-A1 | PIPERAZINE DERIVATIVES FOR THE TREATMENT OF HIV INFECTIONS | PFIZER LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041626-A1 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | MASP2, SERPINB1, SIGLEC7 | MEN1 3930/4885KMT2A 4322/4885SLC22A6 1823/4885 |
| US-20210371413-A1 | POLYCYCLIC AMIDES AS CYTOTOXIC AGENTS | PBRM1, NFATC1, ACIN1 | MEN1 1506/4885KMT2A 957/4885SLC22A6 2811/4885 |
| US-20050043300-A1 | Piperazine derivatives | CD4, CCR5, RRP15 | MEN1 4800/4885KMT2A 2921/4885SLC22A6 3490/4885 |
| US-20120329755-A1 | GLYCOMIMETIC INHIBITORS OF THE PA-IL LECTIN, PA-IIL LECTIN OR BOTH THE LECTINS FROM PSEUDOMONAS | MASP2, SERPINB1, SIGLEC7 | MEN1 3930/4885KMT2A 4322/4885SLC22A6 1823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.