Water

Water

SCHEMBL57587

O.O.S

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11566091 1.00
Water SCHEMBL9405278 1.00
Water SCHEMBL5797904 1.00
Water SCHEMBL19953492 1.00
Water SCHEMBL20566053 1.00
Water SCHEMBL49579 1.00
Water SCHEMBL3841401 1.00
Water SCHEMBL1941845 1.00 OXTR (0.50)
Water SCHEMBL1282691 1.00
Water SCHEMBL28721160 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117429105-A Preparation method of composite rubber sealing element 际华橡胶工业有限公司 2024-01-23 CN claimed
WO-2023225764-A1 METHOD FOR PRODUCING SURFACE-MODIFIED MICRO-FIBRILLATED CELLULOSE DÄTWYLER SCHWEIZ AG (CH) 2023-11-30 WO claimed
CN-116282100-A Laminar double-metal hydroxide carbonyl sulfide hydrolysis catalyst rich in surface defects, preparation method and application thereof 北京化工大学 2023-06-23 CN claimed
EP-2935460-B1 MOBILE ELECTRONIC DEVICE SOLVAY SPECIALTY POLYMERS USA (US) 2020-08-26 EP claimed
CN-110803952-A Crop stem and leaf surface heavy metal resistance control selenium-rich fertilizer capable of increasing crop yield and application method thereof 刘俐 2020-02-18 CN claimed
CN-105896594-B Multi-energy complementation system with cloud management function 上海能辉科技股份有限公司 2018-10-12 CN claimed
US-9988494-B2 Method for forming a high molecular weight polyarylene sulfide TICONA LLC (US) 2018-06-05 US claimed
CN-105221847-B A kind of gas hydrates pipeline and decomposer 常州大学 2017-09-08 CN claimed
CN-106147245-A Good stability of the utility model of the sbs modified asphalt preparation method of 西安旭皓环保科技有限责任公司 2016-11-23 CN claimed
US-20160244568-A1 Method for Forming a High Molecular Weight Polyarylene Sulfide TICONA LLC 2016-08-25 US claimed
WO-1992000367-A1 IMPROVED SULFURIZED OLEFIN EXTREME PRESSURE/ANTIWEAR ADDITIVES AND COMPOSITIONS THEREOF MOBIL OIL CORPORATION (US) 1992-01-09 WO claimed
EP-0448194-A2 Process for production of polyarylenesulfides KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-09-25 EP claimed
US-5019220-A Forming alkaline slurry; adding oxidizer and azide MORTON INTERNATIONAL, INC. (US) 1991-05-28 US claimed
EP-0409496-A2 Microporous membranes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-01-23 EP claimed
US-4490522-A REACTING POLYHALOGENATED AROMATIC COMPOUND WITH ALKALI METAL SULFIDE IN PRESENCE OF OXYALKYLENE COMPOUND DAINIPPON INK & CHEMICALS, INC. (JP) 1984-12-25 US claimed
US-4228761-A Method for coating a polymeric article with a thermochromic paint RAYCHEM CORPORATION (US) 1980-10-21 US claimed
US-4210526-A Desulfurizing fossil fuels SWANSON ROLLAN 1980-07-01 US claimed
US-4160721-A De-sulfurization of petroleum residues using melt of alkali metal sulfide hydrates or hydroxide hydrates SWANSON ROLLAN 1979-07-10 US claimed
US-4121011-A Polymeric article coated with a thermochromic paint RAYCHEM CORPORATION (US) 1978-10-17 US claimed
US-4105583-A THERMOCHROMIC PAINT FOR USE ON PLASTIC SUBSTRATES RAYCHEM CORPORATION (US) 1978-08-08 US claimed