Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.58 |
| ▸ | ADAM17 | P78536 | 13/20 | 0.58 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762105 | 0.91 | MMP1 (0.48) | MMP1ADAM17MMP3MMP9MMP13 | |
| SCHEMBL5758586 | 0.91 | MMP1 (0.59) | MMP1ADAM17MMP3MMP9MMP13 | |
| SCHEMBL5760495 | 0.89 | ADAM17 (0.61) | MMP1ADAM17MMP3MMP13 | |
| SCHEMBL7111222 | 0.86 | MMP1 (0.66) | MMP1ADAM17MMP3MMP9MMP13 | |
| SCHEMBL5761953 | 0.83 | MMP1 (0.41) | MMP1ADAM17MMP3MMP9MMP13 | |
| SCHEMBL5761758 | 0.82 | L3MBTL1 (0.44) | MMP1ADAM17MMP13 | |
| SCHEMBL5757107 | 0.81 | ADAM17 (0.51) | MMP1ADAM17MMP3MMP9MMP13 | |
| SCHEMBL5760549 | 0.80 | ALDH1A1 (0.47) | MMP1ADAM17 | |
| SCHEMBL5760551 | 0.79 | MMP1 (0.75) | MMP1ADAM17 | |
| SCHEMBL6237935 | 0.78 | MMP1 (0.52) | MMP1ADAM17MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104403-B1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PROD INC (US) | 2006-05-10 | — | — | EP | claimed |