Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813939 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNAL3MBTL1HSD17B10CPT2 | |
| Oxalic Acid SCHEMBL27626947 | 0.70 | PPARG (0.40) | ALDH1A1LMNAL3MBTL1HSD17B10DRD4 | |
| SCHEMBL6184871 | 0.70 | KDM4E (0.44) | DRD4KDM4ESLC6A7POLB | |
| SCHEMBL186850 | 0.68 | CCR2 (0.40) | LMNACPT2CPT1ACPT1BPOLB | |
| SCHEMBL3397553 | 0.67 | PHGDH (0.54) | ALDH1A1MAPTTSHRKDM4ENPSR1 | |
| SCHEMBL13980013 | 0.66 | MEN1 (0.43) | ALDH1A1LMNADRD4MAPTKDM4E | |
| SCHEMBL5120102 | 0.64 | HTR2C (0.57) | POLBHRH4HTR2C | |
| SCHEMBL10853139 | 0.63 | GOT1 (0.41) | LMNADRD4MAPTHTR2CSRPK1 | |
| SCHEMBL8074288 | 0.62 | HTR2C (0.44) | SLC6A7MGLLHTR2CGRIN1GRIN2B | |
| SCHEMBL4005423 | 0.61 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1HSD17B10DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513835-B1 | PIPERAZINYLACYLPIPERIDINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2006-08-16 | — | — | EP | disclosed |