Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10673707 | 0.94 | HTR6 (0.48) | HTR6FFAR2PIK3CAALDH1A1LMNA | |
| SCHEMBL8989589 | 0.82 | HSD11B1 (0.37) | ALDH1A1 | |
| SCHEMBL19318751 | 0.81 | GAA (0.54) | FFAR2ALDH1A1GAACA12CA1 | |
| SCHEMBL7266457 | 0.76 | LMNA (0.41) | LMNAGAATDP1CA12CA1 | |
| SCHEMBL19318729 | 0.76 | GAA (0.52) | FFAR2ALDH1A1GAACA12CA1 | |
| SCHEMBL8031497 | 0.75 | HSD11B1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL16718944 | 0.74 | GAA (0.50) | FFAR2ALDH1A1TSHRGAAHSD17B10 | |
| SCHEMBL22548445 | 0.74 | GAA (0.50) | FFAR2ALDH1A1TSHRGAAHSD17B10 | |
| SCHEMBL11148487 | 0.73 | HSD11B1 (0.46) | ALDH1A1TDP1 | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.69 | HTR6 (1.00) | HTR6ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014096374-A1 | PROCESS FOR THE SYNTHESIS OF PYRROLIDINES AND PYRROLES | SANDOZ AG (CH) | 2014-06-26 | — | — | WO | disclosed |
| US-20060247286-A1 | Oxazolidinone antibiotics and derivatives thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1656357-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005005399-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |
| EP-0819981-B1 | Radiation sensitive resin composition | JSR CORP (JP) | 2002-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247286-A1 | Oxazolidinone antibiotics and derivatives thereof | OXA1L, RORC, IL17A | HTR6 4743/4885FFAR2 1795/4885PIK3CA 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.