Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 10/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764971 | 0.85 | PLA2G1B (0.40) | POLBALDH1A1MAPT | |
| SCHEMBL5764508 | 0.85 | PPARG (0.40) | ABL1SRCPOLBALDH1A1KDM4E | |
| SCHEMBL5764673 | 0.84 | LMNA (0.37) | POLBHTTMAPT | |
| SCHEMBL5764178 | 0.81 | MAPT (0.40) | RXFP1ABL1SRCPOLBALDH1A1 | |
| SCHEMBL5765021 | 0.79 | GAA (0.38) | CYP2C9POLBALDH1A1KDM4EHTT | |
| SCHEMBL5763976 | 0.79 | PLA2G2A (0.40) | ALOX5APKIF11CYP2C9 | |
| SCHEMBL5766775 | 0.72 | PLA2G2A (0.40) | ALDH1A1KDM4EMAPT | |
| SCHEMBL5765497 | 0.70 | PLA2G2A (0.47) | — | |
| SCHEMBL5762171 | 0.70 | PLA2G1B (0.42) | POLBALDH1A1KDM4EMAPT | |
| SCHEMBL5763931 | 0.69 | HSP90AA1 (0.40) | POLBHSP90AA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |