Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 7/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764508 | 0.87 | PPARG (0.40) | PLA2G2APOLBPPARGALDH1A1MAPT | |
| SCHEMBL5763363 | 0.85 | ALOX5AP (0.42) | POLBALDH1A1MAPT | |
| SCHEMBL5762171 | 0.85 | PLA2G1B (0.42) | PLA2G1BPLA2G2AFAAHPOLBSQOR | |
| SCHEMBL5762692 | 0.80 | PLA2G2A (0.52) | PLA2G1BPLA2G2APLA2G10PLA2G5 | |
| SCHEMBL5765021 | 0.80 | GAA (0.38) | PLA2G1BPLA2G2APOLBALDH1A1MAPT | |
| SCHEMBL5764178 | 0.80 | MAPT (0.40) | PLA2G2APOLBALDH1A1MAPT | |
| SCHEMBL5764583 | 0.79 | ALDH1A1 (0.36) | PLA2G2APOLBALDH1A1MAPT | |
| SCHEMBL2157014 | 0.75 | PLA2G2A (0.52) | PLA2G1BPLA2G2APLA2G10PLA2G5 | |
| SCHEMBL5766775 | 0.75 | PLA2G2A (0.40) | PLA2G2AFAAHALDH1A1MAPT | |
| SCHEMBL5763475 | 0.72 | PLA2G2A (0.61) | PLA2G1BPLA2G2APLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |