Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767548 | 0.89 | RAB9A (0.33) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5736358 | 0.87 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNAHTT | |
| SCHEMBL5755390 | 0.86 | P2RX7 (0.32) | RORCP2RX7 | |
| SCHEMBL5756968 | 0.83 | CRHR1 (0.39) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL4765020 | 0.80 | POLB (0.33) | POLBMAPTHPGDP2RX7 | |
| Succinic Acid SCHEMBL5757273 | 0.79 | HRH3 (0.36) | ALDH1A1KCNH2HDAC6SSTR3SRD5A2 | |
| SCHEMBL5733066 | 0.79 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL5754230 | 0.77 | WDR5 (0.33) | P2RX7 | |
| SCHEMBL5756080 | 0.77 | KCNH2 (0.40) | KCNH2 | |
| SCHEMBL4775977 | 0.76 | TBK1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |