Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200688 | 0.77 | PPARA (0.42) | — | |
| SCHEMBL5780394 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL5262506 | 0.76 | EPHX2 (0.33) | — | |
| SCHEMBL5764439 | 0.74 | MAPT (0.33) | ALOX5MAPT | |
| SCHEMBL5781491 | 0.71 | ACE (0.37) | — | |
| SCHEMBL4478553 | 0.69 | ALOX5 (0.40) | ALOX5 | |
| SCHEMBL5266526 | 0.67 | — | — | |
| SCHEMBL5740879 | 0.67 | PTPN2 (0.36) | — | |
| SCHEMBL5743320 | 0.67 | KEAP1 (0.35) | ALOX5 | |
| SCHEMBL4824304 | 0.66 | ICMT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006525365-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1620422-A2 | PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2004099170-A2 | PHENYL SUBSTITUTED CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |