Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ARF6 | P62330 | 1/20 | 0.38 |
| ▸ | MAP2 | P11137 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737188 | 0.86 | GPR35 (0.41) | CCR1DHODHARF6MAP2GPR35 | |
| SCHEMBL5739744 | 0.85 | SCD (0.42) | DHODHGPR35MEN1KMT2A | |
| SCHEMBL5738353 | 0.79 | ALDH1A1 (0.42) | HPGDMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL5738604 | 0.73 | MAOB (0.40) | HPGDMEN1GAAKMT2A | |
| SCHEMBL5736875 | 0.72 | MAPT (0.41) | LMNAHPGDMEN1GAAKMT2A | |
| SCHEMBL13168625 | 0.67 | MCL1 (0.63) | DHODHGPR17 | |
| SCHEMBL4996302 | 0.67 | KDM4E (0.48) | MAP2HPGDGPR17MEN1KMT2A | |
| SCHEMBL8545084 | 0.66 | S1PR1 (0.42) | — | |
| SCHEMBL6093097 | 0.66 | SERPINE1 (0.51) | — | |
| SCHEMBL7003912 | 0.66 | LTB4R2 (0.43) | LMNAHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |