Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738764 | 0.92 | MAOB (0.42) | SCDPPARGUSP2POLBEDNRA | |
| SCHEMBL5738353 | 0.89 | ALDH1A1 (0.42) | SCDPPARGPOLBKDM4EMEN1 | |
| SCHEMBL5767326 | 0.85 | CCR1 (0.39) | DHODHMEN1KMT2AGPR35 | |
| SCHEMBL5738604 | 0.83 | MAOB (0.40) | SCDPOLBKDM4EMEN1KMT2A | |
| SCHEMBL5736875 | 0.82 | MAPT (0.41) | SCDUSP2POLBEDNRAKDM4E | |
| SCHEMBL5737188 | 0.80 | GPR35 (0.41) | DHODHGPR35 | |
| SCHEMBL7005265 | 0.78 | MAPT (0.44) | POLBMCL1KDM4EKMT2AGPR35 | |
| SCHEMBL7003912 | 0.76 | LTB4R2 (0.43) | SCDPPARGUSP2POLBEDNRA | |
| Trifluoroacetic Acid SCHEMBL7397464 | 0.71 | PTGDR2 (0.37) | PTGDR2DHODHKDM4EMEN1KMT2A | |
| SCHEMBL7003961 | 0.70 | SCD (0.41) | SCDPPARGUSP2POLBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |