Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738353 | 0.92 | ALDH1A1 (0.42) | MAPTMEN1KMT2APTGESPOLB | |
| SCHEMBL5738764 | 0.88 | MAOB (0.42) | MAOBMAPTMEN1KMT2APOLB | |
| SCHEMBL5736875 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2AGAAPTGES | |
| SCHEMBL5739744 | 0.83 | SCD (0.42) | MEN1KMT2APOLBKDM4ESCD | |
| SCHEMBL7003912 | 0.80 | LTB4R2 (0.43) | MAPTMEN1KMT2APTGESPOLB | |
| SCHEMBL5767326 | 0.73 | CCR1 (0.39) | MEN1KMT2AGAAHPGD | |
| SCHEMBL6092341 | 0.72 | PPARG (0.54) | MAOBKMT2A | |
| SCHEMBL7005935 | 0.71 | ALOX5 (0.45) | MAPTMEN1KMT2AGAAPTGES | |
| SCHEMBL2810771 | 0.69 | HTR6 (0.56) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7002412 | 0.69 | ALDH1A1 (0.39) | MAPTMEN1KMT2AGAAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |