Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771962 | 0.96 | MMP1 (0.34) | MMP1MMP9MMP13KMT2AHTR6 | |
| SCHEMBL5771246 | 0.82 | MMP1 (0.42) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL5770229 | 0.81 | HTR6 (0.34) | MMP1MMP9MMP13KMT2AHTR6 | |
| SCHEMBL5771712 | 0.78 | ABCB1 (0.42) | — | |
| SCHEMBL5772320 | 0.78 | ABCB1 (0.42) | — | |
| SCHEMBL5771968 | 0.78 | MMP1 (0.44) | MMP1MMP9MMP13MMP2MMP3 | |
| SCHEMBL5773477 | 0.74 | ABCB1 (0.43) | KMT2A | |
| SCHEMBL5773719 | 0.74 | ABCB1 (0.43) | KMT2A | |
| SCHEMBL5771487 | 0.69 | KMT2A (0.33) | MMP9KMT2ATAS2R14CASP1CASP3 | |
| SCHEMBL5771242 | 0.68 | MMP1 (0.38) | MMP1MMP9MMP13MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637518-A2 | Inhibitors of aspartyl protease | Vertex Pharmaceuticals Incorporated (US) | 2006-03-22 | — | — | EP | disclosed |