Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773900 | 0.94 | CYP1A2 (0.52) | L3MBTL1NPC1RAB9AKCNH2ALDH1A1 | |
| SCHEMBL5774072 | 0.88 | LMNA (0.54) | RAB9ALMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5773408 | 0.86 | LMNA (0.48) | NPC1RAB9ALMNAHPGDTSHR | |
| SCHEMBL5776524 | 0.84 | EPHX2 (0.43) | KCNH2CYP2C9CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL5776587 | 0.83 | LMNA (0.40) | NPC1RAB9ALMNAHPGDTSHR | |
| Trifluoroacetic Acid SCHEMBL5774844 | 0.82 | HDAC4 (0.40) | LMNAKCNH2ALDH1A1KMT2AMEN1 | |
| SCHEMBL5777386 | 0.81 | LMNA (0.47) | LMNAALDH1A1KMT2AMEN1GAA | |
| Trifluoroacetic Acid SCHEMBL5773568 | 0.81 | EPHX2 (0.52) | KCNH2KMT2AMEN1HPGDGAA | |
| Trifluoroacetic Acid SCHEMBL5771354 | 0.81 | ALDH1A1 (0.49) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5775822 | 0.81 | HPGD (0.49) | LMNAALDH1A1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | MOMOSE YU | 2006-04-20 | — | — | US | disclosed |
| US-7022725-B2 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20040048908-A1 | Isoxazole derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1340749-A1 | ISOXAZOLE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084690-A1 | Isoxazole derivatives | INSR, GPR119, INSRR | L3MBTL1 2718/4885NPC1 2417/4885RAB9A 3076/4885 |
| US-20040048908-A1 | Isoxazole derivatives | GPR119, INSR, IRS1 | L3MBTL1 1898/4885NPC1 1770/4885RAB9A 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.