Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 12/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272893 | 0.85 | KCNH2 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL5773652 | 0.84 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5777366 | 0.81 | LMNA (0.47) | SLC2A1KCNH2SIGMAR1KMT2A | |
| SCHEMBL5775396 | 0.80 | KCNH2 (0.49) | SLC2A1KCNH2SIGMAR1HTR1A | |
| SCHEMBL5772116 | 0.79 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL5776996 | 0.79 | SLC2A1 (0.54) | SLC2A1KCNH2HTR1A | |
| SCHEMBL5775045 | 0.79 | KCNH2 (0.52) | SLC2A1KCNH2SIGMAR1 | |
| SCHEMBL5778699 | 0.78 | SLC2A1 (0.58) | SLC2A1KCNH2SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL5772802 | 0.78 | SLC2A1 (0.48) | SLC2A1KCNH2SIGMAR1MEN1KMT2A | |
| SCHEMBL5777778 | 0.78 | SLC2A1 (0.47) | SLC2A1KCNH2SIGMAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |