Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHAT | P28329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329192 | 0.83 | MAOA (0.46) | CYP2A6ALDH1A1HTR2ATAAR1LOXL2 | |
| SCHEMBL8668115 | 0.81 | MAOA (0.45) | CYP2A6ALDH1A1HTR2ATAAR1LOXL2 | |
| SCHEMBL5999151 | 0.79 | ALDH1A1 (0.43) | CYP2A6ALDH1A1MAOBTSHRMAOA | |
| SCHEMBL8154332 | 0.78 | ALDH1A1 (0.48) | CYP2A6ALDH1A1MAOBTSHRMAOA | |
| SCHEMBL787443 | 0.78 | — | — | |
| SCHEMBL4997007 | 0.75 | HSD17B10 (0.48) | CYP2A6HTR2ATAAR1MAOBTSHR | |
| SCHEMBL1536706 | 0.75 | IDO1 (0.54) | HTR2AMAOBMAOACYP19A1IDO1 | |
| SCHEMBL1829198 | 0.75 | IDO1 (0.54) | HTR2AMAOBMAOACYP19A1IDO1 | |
| SCHEMBL3650173 | 0.75 | TAAR1 (0.44) | HTR2ATAAR1LOXL2MAOB | |
| SCHEMBL5682418 | 0.75 | IDO1 (0.54) | HTR2AMAOBMAOACYP19A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108431298-B | Copper or copper alloy article containing surface-modified polyester resin and method for producing same | 株式会社新技术研究所 | 2019-06-21 | — | — | CN | claimed |
| CN-106145148-B | A method of preparing multi-stage porous Titanium Sieve Molecular Sieve | 中国石油化工股份有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-109369613-A | A kind of diamine compounds being used to prepare aligning agent for liquid crystal and its application | 中节能万润股份有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-105315886-B | Hybrid coating and relevant applying method | 波音公司 | 2018-12-07 | — | — | CN | claimed |
| CN-108068419-A | A kind of lignin modified asphalt waterproof roll and preparation method thereof | 广西武宣金牌防水材料科技有限公司 | 2018-05-25 | — | — | CN | claimed |
| CN-105461930-B | A kind of antifouling coating composition and its preparation and the application in low-surface-energy anti-fouling paint | 上海华谊精细化工有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-107987726-A | A kind of pitch mildewproof waterproof coating and its production method for bridge construction | 广西武宣金牌防水材料科技有限公司 | 2018-05-04 | — | — | CN | claimed |
| CN-105801865-B | A kind of phosphorus-nitrogen containing cage modle polysilsesquioxane and preparation method thereof | 合肥学院 | 2018-04-24 | — | — | CN | claimed |
| CN-107360718-A | Antireflection film and method for producing same | 株式会社LG化学 | 2017-11-17 | — | — | CN | claimed |
| CN-107254132-A | A kind of stable type acrylic diamond and preparation method thereof | 苍南县通普工艺礼品有限公司 | 2017-10-17 | — | — | CN | claimed |
| CN-107177250-A | A kind of environment protective nano-paint and preparation method thereof | 龚大秀 | 2017-09-19 | — | — | CN | claimed |
| CN-107163467-A | A kind of acrylic diamond of strong printing opacity and preparation method thereof | 苍南县通普工艺礼品有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-107129651-A | Strong acrylic diamond of a kind of stability and preparation method thereof | 苍南县通普工艺礼品有限公司 | 2017-09-05 | — | — | CN | claimed |
| US-20110166144-A1 | Pyrimidotriazinediones and Pyrimidopyrimidinediones and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-07-07 | — | — | US | claimed |
| CN-1950477-B | Two-component adhesive/sealant | HENKEL AG & CO KGAA | 2011-01-19 | — | — | CN | claimed |
| WO-2010014798-A2 | PYRIMIDOTRIAZINEDIONES AND PYRIMIDOPYRIMIDINEDIONES AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-02-04 | — | — | WO | claimed |
| CN-1950477-A | Two-component adhesive/sealant | HENKEL KGAA (DE) | 2007-04-18 | — | — | CN | claimed |
| US-6686373-B2 | ANALGESICS; ANTIINFLAMMATORY AGENT | WARNER-LAMBERT COMPANY LLC | 2004-02-03 | — | — | US | claimed |
| US-20030130277-A1 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | KAWAMURA KIYOSHI (JP) | 2003-07-10 | — | — | US | claimed |
| EP-1310498-A2 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PFIZER INC. (US) | 2003-05-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130277-A1 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PRKCB, PRKCA, PRKCG | CYP2A6 3310/4885ALDH1A1 3069/4885HTR2A 1518/4885 |
| US-20110166144-A1 | Pyrimidotriazinediones and Pyrimidopyrimidinediones and Methods of Using the Same | DPYD, TYMP, DHFR | CYP2A6 684/4885ALDH1A1 245/4885HTR2A 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.