Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773019 | 0.88 | RXRA (0.46) | FABP4RXRARXRBRXRGPTGS1 | |
| SCHEMBL5775162 | 0.84 | FFAR4 (0.45) | NTRK1KDM4EALDH1A1 | |
| SCHEMBL5772957 | 0.76 | POLB (0.55) | RXRARXRBRXRGPOLBKDM4E | |
| SCHEMBL15716269 | 0.72 | NTRK1 (0.53) | NTRK1 | |
| SCHEMBL11635985 | 0.70 | PTGS2 (0.49) | PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL1094177 | 0.70 | PTGS2 (0.47) | NPC1RAB9APTGS1PTGS2KDM4E | |
| SCHEMBL11640395 | 0.70 | PTGS2 (0.47) | PTGS1PTGS2ALDH1A1 | |
| SCHEMBL11635414 | 0.70 | PTGS2 (0.47) | PTGS1PTGS2POLBKDM4EPOLQ | |
| SCHEMBL10479421 | 0.70 | FABP4 (0.56) | FABP4NPC1RAB9ARXRARXRB | |
| SCHEMBL13858506 | 0.69 | NTRK1 (0.55) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885883-B1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-6187774-B1 | N-PIPERAZINYLALKYLINDAZOLE DERIVATIVES; PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0885883-A1 | FUSED HETEROCYCLIC COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |